West African manuscripts are numerous and varied in forms and contents. There are thousands of them across West Africa. A significant portion of them are documents written in Arabic and Ajami (African languages written in Arabic script). They deal with both religious and nonreligious subjects. The development of these manuscript traditions dates back to the early days of Islam in West Africa, in the 11th century. In addition to these Arabic and Ajami manuscripts, there have been others written in indigenous scripts. These include those in the Vai script invented in Liberia; Tifinagh, the traditional writing system of the Amazigh (Berber) people; and the N’KO script invented in Guinea for Mande languages. While the writings in indigenous scripts are rare less numerous and widespread, they nonetheless constitute an important component of West Africa’s written heritage. Though the efforts devoted to the preservation of West African manuscripts are limited compared to other world regions, interest in preserving them has increased. Some of the initial preservation efforts of West African manuscripts are the collections of colonial officers. Academics later supplemented these collections. These efforts resulted in important print and digital repositories of West African manuscripts in Africa, Europe, and America. Until recently, most of the cataloguing and digital preservation efforts of West African manuscripts have focused on those written in Arabic. However, there has been an increasing interest in West African manuscripts written in Ajami and indigenous scripts. Important West African manuscripts in Arabic, Ajami, and indigenous scripts have now been digitized and preserved, though the bulk remain uncatalogued and unknown beyond the communities of their owners.